Theme 02
CBD & medical cannabis
On the rise worldwide and scientifically recognised
Definition
What is CBD?
CBD stands for cannabidiol (non-psychoactive) and is one of the approximately 100 cannabinoids from the cannabis plant.
In November 2020 the European Court of Justice classified CBD as harmless — in line with the WHO recommendation of 2018.
Cannabinoid system
The endocannabinoid system
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01
Discovery in 1963
Prof. Dr. Mechoulam (Israel) isolated CBD in 1963.
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02
Receptors CB1 and CB2
The best-known receptors are CB1 and CB2.
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03
Binding
Cannabinoids bind to these receptors.
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Regulation
Regulation of overactive neurotransmitters.
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05
Homeostasis
Maintaining and restoring homeostasis.
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Humans and animals
The system is present in humans and animals.
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Medical use
Medical cannabis in practice
Medical cannabis is approved in many countries. In Germany, health insurers have covered the costs under certain conditions since 2017, and since April 2024 medical cannabis is no longer classified as a narcotic. According to the Federal Institute for Drugs and Medical Devices, imports rose from around 71 tonnes in 2024 to 201 tonnes in 2025.
Indications include chronic pain, spasticity in multiple sclerosis, severe forms of epilepsy and side effects of cancer and HIV therapies.
In the USA, 41 states allow medical use; since 28 April 2026 the DEA lists cannabis from state medical programmes in Schedule III. Sources: BfArM, DISA, Federal Register.
Approved medicines
Evidence and approval
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Sativex
Approved for multiple sclerosis.
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Epidiolex
Approved for two forms of epilepsy.
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Over 500 studies
Evidence-based clinical studies across medical disciplines.